Urolithin A promotes p62-dependent lysophagy to prevent acute retinal neurodegeneration.

Juan Ignacio Jiménez-LoygorriÁlvaro Viedma-PoyatosRaquel Gómez-SintesPatricia Boya

Published in: Molecular neurodegeneration (2024)

Collectively, these data highlight a novel putative application of UA in the treatment of AMD whereby it bypasses lysosomal defects by promoting p62-dependent lysophagy to sustain proteostasis.

Keyphrases

liver failure
optical coherence tomography
electronic health record
diabetic retinopathy
respiratory failure
big data
drug induced
machine learning
hepatitis b virus
optic nerve
intensive care unit