Regression of Chiari malformation type 2 following early postnatal meningomyelocele repair-a retrospective observation from an institutional series of patients.
Radek FričMona Kristiansen BeyerBernt Johan Due-TønnessenPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2024)
In our experience, spontaneous regression of CM2 in children with postnatally repaired MMC occurs quite rarely. Pathophysiological mechanisms behind the development of CM2 in children with MMC remain unclear, but our observation supports the hypothesis of an association between the downward displacement of the hindbrain and the low intraspinal pressure secondary to CSF leakage in children born with MMC.