Gene discoveries in autism are biased towards comorbidity with intellectual disability.

Matthew JensenCorrine SmolenSanthosh D Girirajan

Published in: Journal of medical genetics (2020)

Pathogenic de novo variants disrupting autism-associated genes contribute towards autism and ID comorbidity, while other genetic factors are likely to be causal for high-functioning autism.

Keyphrases

intellectual disability
autism spectrum disorder
genome wide
copy number
dna methylation