Perioperative interruption of direct oral anticoagulants and vitamin K antagonists in patients with atrial fibrillation: A comparative analysis.

Joseph R ShawTinghua ZhangGrégoire Le GalJames DouketisMarc Carrier

Published in: Research and practice in thrombosis and haemostasis (2020)

The perioperative interruption of VKAs may be associated with higher postoperative major bleeding rates as compared to DOACs. Careful postoperative reinitiation and monitoring of VKA anticoagulation may be warranted following surgical procedures.

Keyphrases

direct oral anticoagulants
atrial fibrillation
patients undergoing
venous thromboembolism
cardiac surgery
acute kidney injury