Gm6377 suppressed SP 2/0 xenograft tumor by down-regulating Myc transcription.

B ZhaiC HouR XuY FangN MaC XingX WangH XiaoG ChenG HanRenxi Wang

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2020)

These results suggest that Gm6377 suppresses myeloma SP 2/0 cell growth by suppressing Myc. Thus, modulation of Gm6377 may be a potential therapeutic way to treat MM.

Keyphrases

transcription factor
signaling pathway
multiple myeloma
newly diagnosed