An overview of biological applications and fundamentals of new inlet and vacuum ionization technologies.
Sarah TrimpinDarrell D MarshallSantosh KarkiSara MadarshahianKhoa HoangAnil K MeherMilan PophristicAlicia L RichardsChristopher B LietzJoshua L FischerEfstathios A EliaBeixi WangVincent S PagnottiCorinne A LutomskiTarick J El-BabaI-Chung LuJames Wager-MillerKen MackieCharles N McEwenEllen D InutanPublished in: Rapid communications in mass spectrometry : RCM (2020)
Examples are provided highlighting the exceptional analytical capabilities associated with the novel ionization processes in MS that reduce operational complexity while increasing speed and robustness, achieving mass spectra with low background for improved sensitivity, suggesting the potential of this simple ionization technology to drive MS into areas currently underserved, such as clinical and medical applications.