Knee pain as a predictor of structural progression over 4 years: data from the Osteoarthritis Initiative, a prospective cohort study.
Yuanyuan WangAndrew J TeichtahlFrançois AbramSultana Monira HussainJean-Pierre PelletierFlavia M CicuttiniJohanne Martel-PelletierPublished in: Arthritis research & therapy (2018)
Knee pain over 1 year predicted accelerated cartilage volume loss and increased risk of incident and progressive ROA. Early management of knee pain and controlling knee pain over time by targeting the underlying mechanisms may be important for preserving knee structure and reducing the burden of knee OA.
Keyphrases
- total knee arthroplasty
- knee osteoarthritis
- chronic pain
- pain management
- anterior cruciate ligament
- anterior cruciate ligament reconstruction
- neuropathic pain
- cardiovascular disease
- multiple sclerosis
- type diabetes
- quality improvement
- spinal cord injury
- electronic health record
- risk factors
- postoperative pain
- extracellular matrix
- artificial intelligence