A clinical and pathophysiological approach to traumatic brain injury-induced pituitary dysfunction.

Published in: Pituitary (2019)

The underlying pathophysiology responsible for post-TBI pituitary dysfunction is not clear. The main proposed mechanisms are vascular injury, direct traumatic injury to the pituitary gland, genetic susceptibility, autoimmunity, and transient medication effects.

Keyphrases

traumatic brain injury
growth hormone
oxidative stress
spinal cord injury
diabetic rats
high glucose
healthcare
severe traumatic brain injury
genome wide
copy number
emergency department
gene expression
drug induced
dna methylation
adverse drug
brain injury