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Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome.

Hussam TabajaKelsey L JensenChristina G RiveraAnisha MisraRajiv K PruthiPaschalis Vergidis
Published in: Open forum infectious diseases (2022)
GATA2 mutation can result in profoundly reduced monocytes, dendritic cells, natural killer cells, and B cells, and is associated with a predisposition for recurrent and disseminated nontuberculous mycobacterial (NTM) infections and myelodysplasias. Herein, we describe a unique case of 3 simultaneous disseminated NTM infections in a patient with GATA2 mutations.
Keyphrases
  • dendritic cells
  • transcription factor
  • natural killer cells
  • immune response
  • mycobacterium tuberculosis
  • case report