Effects of latroeggtoxin-VI on dopamine and α-synuclein in PC12 cells and the implications for Parkinson's disease.

Dianmei YuHaiyan WangYiwen ZhaiZhixiang LeiMinglu SunSi ChenPanfeng YinXianchun Wang

Published in: Biological research (2024)

All the results demonstrate that LETX-VI promotes the synthesis and release of dopamine in PC12 cells via multiple mechanisms including preventing abnormal α-synuclein accumulation, showing implications in the prevention and treatment of PD.

Keyphrases

uric acid
prefrontal cortex
metabolic syndrome
replacement therapy