Association of Cholesterol and Oxysterols in Adipose Tissue With Obesity and Metabolic Syndrome Traits.

Lucia Baila-RuedaAna CenarroItziar Lamiquiz-MoneoVictoria Marco-BenediGracia-Rubio IreneMaria Carmen Casamayor-FrancoJose M Arbones-MainarFernando CiveiraMartin Laclaustra

Published in: The Journal of clinical endocrinology and metabolism (2022)

Adipose tissue oxysterols are associated with blood insulin and insulin resistance. Tissue cholesterol correlated more with 27-hydroxycholesterol in subcutaneous adipose tissue and with 24S-hydroxycholesterol in visceral adipose tissue. Levels of adipose 24S-hydroxycholesterol seem to be correlated with some metabolic syndrome symptoms and inflammation while adipose 27-hydroxycholesterol could represent some protection against them.

Keyphrases

insulin resistance
adipose tissue
metabolic syndrome
high fat diet
high fat diet induced
polycystic ovary syndrome
type diabetes
glycemic control
skeletal muscle
oxidative stress
cardiovascular disease
low density lipoprotein
cardiovascular risk factors
weight gain