Eczematous drug eruption in psoriasis patients under anti-IL-17A: does IL-22 play a key role?

Matteo Megna Giuseppina CaiazzoM ParisiRuggiero AngeloG CapassoM MascoloD RussoL GalloG FabbrociniMaddalena NapolitanoC Patruno

Published in: Clinical and experimental dermatology (2021)

EDE skin lesions have mainly Th2/Th22 features, with IL-22 playing a major role in the pathogenesis. EDE can be considered as the result of the imbalance towards Th2/Th22 response secondary to the blockade of IL-17A-activity.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
emergency department
prognostic factors
wound healing