Anillin regulates breast cancer cell migration, growth, and metastasis by non-canonical mechanisms involving control of cell stemness and differentiation.
Dongdong WangNayden G NaydenovMikhail G DozmorovJennifer E KoblinskiAndrei I IvanovPublished in: Breast cancer research : BCR (2020)
Our study demonstrates that anillin plays essential roles in promoting breast cancer growth and metastatic dissemination in vitro and in vivo and unravels novel functions of anillin in regulating breast cancer stemness and differentiation.