Computational analysis of cortical neuronal excitotoxicity in a large animal model of neonatal brain injury.

Panagiotis KratimenosAbhya VijRobinson VidvaIoannis KoutroulisMaria Delivoria-PapadopoulosVittorio GalloAaron Sathyanesan

Published in: Journal of neurodevelopmental disorders (2022)

/CaM-Src signaling pathway leading to neuronal injury and provides a feasible framework for drug efficacy studies in translational models of neonatal brain injury for the prevention of intellectual and developmental disabilities.

Keyphrases

brain injury
cerebral ischemia
subarachnoid hemorrhage
signaling pathway
pi k akt
tyrosine kinase
epithelial mesenchymal transition
emergency department
case control
induced apoptosis
blood brain barrier
endoplasmic reticulum stress