Early plasma biomarker dynamic profiles are associated with acute ischemic stroke outcomes.
Manuel CorreiaIsabel SilvaDenis GabrielJoel SimrénAngelo CarneiroSara RibeiroHugo Mota DóriaRicardo VarelaAna Luísa Aires SilvaKarolina MintaRui AntunesRui FelgueirasPedro CastroKaj BlenowRui MagalhãesHenrik ZetterbergMarta Francisca CorràPublished in: European journal of neurology (2022)
Early GFAP, t-tau and NfL rate-of-change in plasma can predict AIS clinical and neuroimaging outcome after successful recanalization. Such dynamic measures match and anticipate neuroimaging predictive capacity, potentially improving AIS patient stratification for treatment, and targeting individualized stroke care.