Risk factors for the development of hospital-acquired pediatric venous thromboembolism-Dealing with potentially causal and confounding risk factors using a directed acyclic graph (DAG) analysis.

Leonardo Rodrigues CamposMaurício PetroliFlavio Roberto SztajnbokElaine Sobral da CostaLeonardo Rodrigues BrandãoMarcelo Gerardin Poirot Land

Published in: PloS one (2020)

The DAG-based approach was useful to clarify the influence of confounders and multiple causalities of HA-VTE. Interestingly, CVC placement-a known thrombotic risk factor highlighted in several studies-was considered a confounder, while LOS, L-asparaginase use and nephrotic syndrome were confirmed as risk factors to HA-VTE. Large confidence intervals are related to the sample size; however, the results were significant.

Keyphrases

venous thromboembolism
risk factors
direct oral anticoagulants
healthcare
emergency department
young adults
case control
convolutional neural network
acute care