Synthesis of hydroxyl-functionalized N-heterocyclic carbene gold(i) complexes and peptide conjugates.
Tobias DiehlMelanie T S KrauseSven UeberleinStefanie BeckerAline TrommerGregor SchnakenburgMarianne EngeserPublished in: Dalton transactions (Cambridge, England : 2003) (2018)
The synthesis and characterization of a series of new cationic gold(i) complexes with hydroxyl-functionalized N-heterocyclic carbene (NHC) ligands is described. They are valuable building blocks for further derivatization: as a first example, coupling with amino acids and a dipeptide, respectively, successfully results in amino acid and peptide conjugates that are hard to obtain by other synthetic routes.