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Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial.

Emma E DavenportTiffany AmariutaMaria Gutierrez-ArcelusKamil SlowikowskiHarm-Jan WestraYang LuoCiyue ShenDeepak A RaoYing ZhangStephen PearsonDavid von SchackJean S BeebeNan BingSally JohnMichael S VincentBaohong ZhangSoumya Raychaudhuri
Published in: Genome biology (2018)
This study highlights the potential to exploit clinical trial data to discover in vivo eQTL interactions with therapeutically relevant environmental variables.
Keyphrases
  • clinical trial
  • phase ii
  • systemic lupus erythematosus
  • open label
  • double blind
  • human health
  • electronic health record
  • phase iii
  • disease activity
  • big data
  • deep learning