Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial.

Emma E DavenportTiffany AmariutaMaria Gutierrez-ArcelusKamil SlowikowskiHarm-Jan WestraYang LuoCiyue ShenDeepak A RaoYing ZhangStephen PearsonDavid von SchackJean S BeebeNan BingSally JohnMichael S VincentBaohong ZhangSoumya Raychaudhuri

Published in: Genome biology (2018)

This study highlights the potential to exploit clinical trial data to discover in vivo eQTL interactions with therapeutically relevant environmental variables.

Keyphrases

clinical trial
phase ii
systemic lupus erythematosus
open label
double blind
human health
electronic health record
phase iii
disease activity
big data
deep learning