Differential expression of PEA3 in odontogenic cysts and tumors.

Khin Mya TunNakarin KitkumthornDusit BumaleeTawepong ArayapisitPuangwan Lapthanasupkul

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2023)

PEA3 overexpression is predominant in unicystic ameloblastomas and conventional ameloblastomas compared to other odontogenic lesions, indicating a pivotal role of PEA3 as a downstream effector of MAPK pathway in these two odontogenic lesions.

Keyphrases

signaling pathway
oxidative stress
regulatory t cells
dendritic cells
pi k akt
immune response
type iii