Splenic ectopic pregnancy refers to the implantation of fertilized ovum in the spleen, which occurs extremely rare. Due to the abundance of splenic blood and its fragile texture, the lethality of ruptured hemorrhage in splenic ectopic pregnancy is higher than that of other ectopic pregnancies. Hence, prompt diagnosis and treatment are critical. Here, we report the case of a 34-year-old woman who was presented with amenorrhea. Computed tomography demonstrated a 1.4-cm solid-cystic lesion in the lower pole of the spleen with patchy and spotty enhancement. Therefore, a laparoscopic splenectomy was performed. Microscopically, the lesion contained placental villous tissues, diagnosing a splenic pregnancy.