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Demethylzeylasteral ameliorates podocyte damage in murine lupus by inhibiting inflammation and enhancing autophagy.

Pan ShenXuan DengZhe ChenMin ChenLiang HanXiaoqi ChenShenghao Tu
Published in: Phytomedicine : international journal of phytotherapy and phytopharmacology (2024)
These findings provide strong evidence for the beneficial effects of DML in LN, suggesting its potential as a novel therapeutic strategy for improving renal function in autoimmune kidney diseases.
Keyphrases
  • oxidative stress
  • signaling pathway
  • systemic lupus erythematosus
  • disease activity
  • multiple sclerosis
  • cell death
  • diabetic nephropathy
  • endoplasmic reticulum stress
  • mouse model
  • high glucose
  • endothelial cells