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Hematological involvement in sarcoidosis: from cytopenias to lymphoma.

Pilar Brito-ZerónElyse E LowerManuel Ramos-CasalsRobert P Baughman
Published in: Expert review of clinical immunology (2023)
The association between sarcoidosis and hematologic involvement isbest understood as a pathogenic continuum, with cytopenias andhematologic neoplasms intertwined due to various etiopathogenicmechanisms. These mechanisms include sarcoid infiltration ofhematopoietic organs, common predisposing immunogenetics for thedevelopment of autoimmune cytopenias and malignancies, and anincreased risk of neoplasm development in patients with autoimmunecytopenias. Collaboration among the main specialties involved in theclinical management of these patients is crucial for an earlymonitoring and management.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • chronic kidney disease
  • newly diagnosed
  • multiple sclerosis
  • peritoneal dialysis
  • prognostic factors
  • diffuse large b cell lymphoma
  • low grade
  • high grade
  • patient reported