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Vitreous levels of vascular endothelial growth factor, stromal cell-derived factor-1α, and angiopoietin-like protein 2 in patients with active proliferative diabetic retinopathy.

Ali KelesKenan SonmezYasemin Ozdamar ErolSema Nur AyyıldızElmas Ogus
Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2020)
High levels of SDF-1α, ANGPTL2 and particularly VEGF seem to be associated with PDR. Since the vitreous levels of ANGPTL2 tend to be higher in eyes with active fibrovascular tractional detachment, vitreous levels of this chemokine seem to be affected by the clinical presentation of vascularly active PDR eyes.
Keyphrases
  • vascular endothelial growth factor
  • diabetic retinopathy
  • optical coherence tomography
  • endothelial cells
  • bone marrow