Cu(OTf) 2 /NBS-Mediated Tandem Reaction of 1-Cinnamyl Alcohol- o -Carboranes via Ring Opening of Oxetane with Arenes: An Alternative Approach for the Synthesis of C-Alkenyl- o -Carboranes.

The Cu(OTf) 2 /NBS-mediated tandem reaction of 1-cinnamyl alcohol- o -carboranes for the synthesis of C-alkenyl- o -carboranes has been developed. Mechanism studies demonstrated that the Cu(OTf) 2 -promoted ring opening of oxetane with electron-rich arenes as soft nucleophiles was involved and was the key step for the transformation. This work provided an alternative strategy for the synthesis of C-alkenyl- o -carboranes, which has an important reference for the synthesis of o -carborane derivatives with diversity.