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Pulmonary melanocytic nevus - A case report with a mutation analysis of common driver oncogenes.

Meiro TanakaMai MatsumuraKoji OkudelaHideaki MitsuiYoko TateishiShigeaki UmedaTakehisa SuzukiChihiro KoikeToshiaki KataokaNaomi KawanoYui KojimaHiroyuki OsawaKenichi Ohashi
Published in: Pathology international (2019)
Nevi are benign melanocytic tumors, and some nevi are considered to develop into malignant melanomas. Most nevi arise in the skin, but nevi occasionally occur in the conjunctiva, esophageal mucosa, or at other sites. Pulmonary melanocytic nevi are extremely rare, and only one case has been reported in the literature. Here, we present a case of pulmonary melanocytic nevus, involving a BRAF gene mutation (V600E), and we discuss the potential significance of this condition as a precursor to pulmonary malignant melanoma.
Keyphrases
  • pulmonary hypertension
  • systematic review
  • soft tissue
  • human health