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Optimizing the genetic prediction of the eye and hair color for North Eurasian populations.

Elena BalanovskaElena LukianovaJanet KagazezhevaAndrey MaurerNatalia LeybovaAnastasiya AgdzhoyanIgor GorinValeria PetrushenkoMaxat ZhabaginVladimir PylevElena KostryukovaOleg Balanovsky
Published in: BMC genomics (2020)
This study demonstrated that precision of the established systems for eye/hair color prediction from a genotype is slightly lower for the populations from the border regions between Europe and Asia that for the West Europeans. However, this precision can be improved if some newly revealed predictive SNPs are added into the panel. We discuss that the replication of these pigmentation-associated SNPs on the independent North Eurasian sample is needed in the future studies.
Keyphrases
  • genome wide
  • tertiary care
  • current status
  • genetic diversity
  • copy number
  • genome wide association
  • case control