Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of 1H-magnetic resonance spectroscopy studies.
Tomomi NakaharaSakiko TsugawaYoshihiro NodaFumihiko UenoShiori HondaMegumi KinjoHikari SegawaNobuaki HondoYukino MoriHonoka WatanabeKazuho NakaharaKazunari YoshidaMasataka WadaRyosuke TarumiYusuke IwataEric PlitmanSho MoriguchiCamilo de la Fuente-SandovalHiroyuki UchidaMasaru MimuraAriel Graff-GuerreroShinichiro NakajimaPublished in: Molecular psychiatry (2021)
Increased glutamatergic metabolite levels and reduced GABA levels indicate that the disruption of excitatory/inhibitory balance may be related to the pathophysiology of schizophrenia-spectrum disorders.
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