The Impact of Signet Ring Cell Differentiation on Outcome in Patients with Esophageal and Gastroesophageal Junction Adenocarcinoma.
Sander J M van HootegemB Mark SmithersDavid C GotleySandra BrosdaIain G ThomsonJanine M ThomasMichael GartsideJan J B van LanschotSjoerd M LagardeBas P L WijnhovenAndrew P BarbourPublished in: Annals of surgical oncology (2019)
SRC differentiation was not independently associated with worse OS in patients with EAC who underwent neoadjuvant therapy and surgery. However, nCRT was associated with greater tumor downstaging and better DFS.