Beta-containing bivalent SARS-CoV-2 protein vaccine elicits durable broad neutralization in macaques and protection in hamsters.
Catherine BerryVincent PavotNatalie G AnosovaMichael KishkoLu LiTim TibbittsAlice RaillardSylviane GautheronSheila CummingsDinesh S BangariSwagata KarCaroline AtyeoYixiang DengGalit AlterCindy GutzeitMarguerite KoutsoukosRoman M ChiczValerie LecouturierPublished in: Communications medicine (2023)
Our findings demonstrate the potential of a Beta-containing bivalent CoV2 preS dTM-AS03 formulation to provide broad and durable immunogenicity, as well as protection against VOC in naïve populations.