Hypertonic saline for traumatic brain injury: a systematic review and meta-analysis.
Nafiseh GharizadehMorteza GhojazadehAmirreza NaseriSanam DolatiFaezeh TarighatHassan SoleimanpourPublished in: European journal of medical research (2022)
HTS can significantly reduce the ICP, which may prevent secondary injury. Also, based on the available evidence, HTS has relatively similar efficacy to Mannitol, which is considered the gold standard therapy for TBI, in boosting patients' neurological condition and reducing mortality rates.