Determining value of Coordinated Registry Networks (CRNs): a case of transcatheter valve therapies.
Gregory PappasJesse BerlinErika Avila-TangJohn CarrollJoseph DrozdaDouglas DumontThomas GrossKathleen HewittAjay KirtaneDavid KongMitchell KrucoffJohn LashingerNellie LewMichael MackFred MasoudiDanica Marinac-DabicRoxanna MehranSharon-Lise NormandElizabeth QuinFred ResnicArt SedrakyanRonald WaksmanLarry WoodChangfu WuTianay ZieglerPublished in: BMJ surgery, interventions, & health technologies (2019)
The CRN method to evidence generation creates value for manufacturers and the broader device ecosystem, demonstrated with this example of the TVT CRN. The public health benefits of evidence created by this CRN outweighs the difference in data quality between traditional clinical studies and the CRN method.