Suppression of Adenosine Deaminase and Xanthine Oxidase Activities by Mineralocorticoid and Glucocorticoid Receptor Blockades Restores Renal Antioxidative Barrier in Oral Contraceptive-Treated Dam.
Olufunto O BadmusEmmanuel D AreolaEleojo BenjaminMatthew A ObekpaTolulope E AdegokeOluwatobi E ElijahAminu ImamOlayemi J OlajideLawrence Aderemi OlatunjiPublished in: Journal of the renin-angiotensin-aldosterone system : JRAAS (2021)
These findings implicate the involvements of GR and MR in renal dysfunctions caused by COC in dams via disrupted glutathione antioxidative barrier.