Comprehensive genetic analysis of donor cell derived leukemia with KMT2A rearrangement.

Rieko TaniguchiHideki MuramatsuYusuke OkunoKyogo SuzukiSatoshi ObuMasahiro NakatochiTeppei ShimamuraYoshiyuki TakahashiYasuo HorikoshiKenichiro WatanabeSeiji Kojima

Published in: Pediatric blood & cancer (2017)

We propose a novel pattern of the molecular pathogenesis of DCL solely involving a genetic mutation acquired after transplant with no identifiable genetic factor related to the donor and recipient.

Keyphrases

genome wide
copy number
acute myeloid leukemia
bone marrow