Paresthesia Predicts Increased Risk of Distal Neuropathic Pain in Older People with HIV-Associated Sensory Polyneuropathy.
Monica M DiazJohn R KeltnerAlan N SimmonsDonald FranklinRaeanne C MooreDavid CliffordAnn C CollierBenjamin B GelmanPh D Christina MarraJ Allen McCutchanSusan MorgelloNed SacktorBrookie BestChristine Fennema NotestineSara Gianella WeibelIgor GrantThomas D MarcotteFlorin VaidaScott LetendreRobert HeatonRonald J EllisPublished in: Pain medicine (Malden, Mass.) (2021)
Paresthesias are a clinically significant predictor of incident pain at follow-up among aging PWH with DSP. Development of new therapies to encourage neuroregeneration might take advantage of this finding to choose individuals likely to benefit from treatment preventing incident pain.