KRAS Mutation in Pediatric Intracranial Germ Cell Tumors.
Chusana KhaimanPiti TechavichitHansamon PoparnKanhatai ChiangthongSupanun LauhasurayotinDarintr SosothikulKanjana ShotelersukChonnipa NantavithyaKetsuda JakchairoongruangJiraporn AmornfaEkkachai KhongkhadueadSakun SantisukwongchoteChinachote TeerapakpinyoShanop ShuangshotPublished in: Asian Pacific journal of cancer prevention : APJCP (2022)
Our study revealed the treatment outcomes of IGCTs in Thai children. The metastatic germinoma patient with KRAS codon 61 mutation had a poor outcome, supporting that Q61L has a clinical correlation with IGCTs.