Login / Signup

Human Enzymes for Organic Synthesis.

Margit WinklerMartina GeierSteven P HanlonBernd NidetzkyAnton Glieder
Published in: Angewandte Chemie (International ed. in English) (2018)
Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism of drugs and xenobiotics. Some of these reactions have been explored on the preparative scale. The major field of application of human enzymes is currently drug development, where they are applied for the synthesis of drug metabolites.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • emergency department
  • risk assessment
  • drug induced