The β 2 -Glycoprotein I/HLA-DR Complex As a Major Autoantibody Target in Obstetric Antiphospholipid Syndrome.
Kenji TanimuraShigeru SaitoMikiya NakatsukaTakeshi NagamatsuTomoyuki FujiiAtsushi FukuiMasashi DeguchiYuki SasagawaNoriko AraseHisashi AraseHideto YamadaPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
The anti-β2 GPI/HLA-DR antibody is frequently associated with RPL. Detection of these autoantibodies is useful in understanding the pathogenesis of RPL. Our findings may provide potential new therapeutic strategies for addressing RPL in patients with obstetric APS.