SARS-CoV-2 N Protein Triggers Acute Lung Injury via Modulating Macrophage Activation and Infiltration in in vitro and in vivo.

Dengming LaiKun ZhuSisi Li Yi XiaoQi XuYi-Sheng SunPingping YaoDaqing MaQiang Shu

Published in: Journal of inflammation research (2023)

SARS-CoV-2 and its N protein but not S protein induced acute lung injury and systemic inflammation, which was closely related to macrophage activation, infiltration and release cytokines.

Keyphrases

sars cov
lipopolysaccharide induced
protein protein
lps induced
adipose tissue
respiratory syndrome coronavirus
amino acid
binding protein
signaling pathway
inflammatory response
diabetic rats
endothelial cells
stress induced