Intraoperative ketamine administration to prevent delirium or postoperative cognitive dysfunction: A systematic review and meta-analysis.

Frédérique HovaguimianC TschoppB Beck-SchimmerM Puhan

Published in: Acta anaesthesiologica Scandinavica (2018)

The effect of ketamine on postoperative delirium remains unclear but its administration may offer some protection towards POCD. Large, well-designed randomised trials are urgently needed to further clarify the efficacy of ketamine on neurocognitive outcomes.

Keyphrases

patients undergoing
pain management
cardiac surgery
clinical trial
hip fracture
open label
bipolar disorder
double blind
acute kidney injury
type diabetes
metabolic syndrome
placebo controlled
insulin resistance