Contrast-associated acute kidney injury: does it really exist, and if so, what to do about it?
Wim VandenbergheEric A J HostePublished in: F1000Research (2019)
For decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent literature questions the existence of AKI induced by contrast, but animal studies clearly showed harmful effects. The occurrence of contrast-associated AKI was likely overestimated in the past because of confounders for AKI. Several strategies have been investigated to reduce contrast-associated AKI but even for the most important one, hydration, there are conflicting data. Even if the occurrence rate of contrast-associated AKI is low, AKI is related to worse outcomes. Therefore, besides limiting contrast agent usage, general AKI preventive measurements should be applied in at-risk patients.
Keyphrases
- acute kidney injury
- cardiac surgery
- magnetic resonance
- contrast enhanced
- risk assessment
- systematic review
- primary care
- ejection fraction
- machine learning
- magnetic resonance imaging
- electronic health record
- skeletal muscle
- metabolic syndrome
- prognostic factors
- high resolution
- insulin resistance
- deep learning
- patient reported outcomes