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Hepatic transcriptome and DNA methylation patterns following perinatal and chronic BPS exposure in male mice.

Axelle BrulportDaniel VaimanElias Bou-MarounMarie-Christine ChagnonLudovic Le Corre
Published in: BMC genomics (2020)
This descriptive study shows an impact of BPS on biological pathways mainly related to an integrative disruption of metabolism (energy metabolism, detoxification, protein and steroid metabolism) and, like most high-throughput studies, contributes to the identification of potential exposure biomarkers.
Keyphrases
  • high throughput
  • dna methylation
  • genome wide
  • single cell
  • gene expression
  • pregnant women
  • rna seq
  • binding protein
  • drug induced
  • small molecule
  • case control
  • network analysis
  • copy number
  • risk assessment