Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept.

Erez EitanTricia Thornton-WellsKatya ElgartEren ErdenEve GershunAmir LevineOlga VolpertMitra AzadehDaniel G Smith

Published in: Extracellular vesicles and circulating nucleic acids (2023)

NDEV isolation by GAP43 and NLGN3 immunocapture offers a robust novel platform for biomarker development in AD, suitable for large-scale validation.

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