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RCC1 functions as a tumor facilitator in clear cell renal cell carcinoma by dysregulating cell cycle, apoptosis, and EZH2 stability.

Yunfei WuZhijie XuXiaoyi ChenGuanghou FuJunjie TianBaiye Jin
Published in: Cancer medicine (2023)
RCC1 could be a potential therapeutic target in ccRCC. The RCC1/EZH2 axis takes part in the development of ccRCC.
Keyphrases
  • cell cycle
  • renal cell carcinoma
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • oxidative stress
  • endoplasmic reticulum stress
  • cell death
  • cell cycle arrest
  • signaling pathway