Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling.

Kenji OhshimaRyo OiDaisuke OkuzakiDaisuke MotookaMasakazu ShinoharaSatoshi NojimaEiichi Morii

Published in: British journal of cancer (2021)

Our findings link mitochondrial membrane potential to Wnt/β-catenin signalling and reveal a previously unrecognised function of the mitochondrial matrix protein C14orf159 as a suppressor of CRC metastasis.

Keyphrases

cell proliferation
oxidative stress
stem cells
epithelial mesenchymal transition
protein protein
amino acid
binding protein
gene expression
genome wide
single cell
human health