Emodin Inhibited Pathological Cardiac Hypertrophy in Response to Angiotensin-Induced Hypertension and Altered the Gut Microbiome.
Levi EvansTori PriceNathaniel HubertJulia MooreYiqui ShenMaheshi AthukoralaSteven FreseKristina Martinez-GurynBradley S FergusonPublished in: Biomolecules (2023)
Our data demonstrate that emodin attenuates pathological hypertrophy in female mice. Future research is needed to dissect if changes in the microbiome contributes to emodin-mediated attenuation in cardiac remodeling.