BRCAness of brain lesions reflects a worse outcome for patients with metastatic breast cancer.
Yumiko IshizukaYoshiya HorimotoHidetaka EguchiFumi MurakamiKatsuya NakaiHiroko OnagiTakuo HayashiTakashi IshikawaMasami AraiJunichiro WatanabePublished in: Breast cancer research and treatment (2023)
In this study, we evaluated BRCAness in brain metastases of breast cancer with the MLPA method, and found that about one-third of patients had BRCAness-positive tumors. The analysis of BRCAness using MLPA has the potential for practical clinical use.