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Absence of TFE3 Immunoexpression in a Spectrum of Cutaneous Mixed Tumors: A Retrospective Pilot Study.

Hatice B ZenginBahadir YildizTatsiana PukhalskayaBruce R Smoller
Published in: Dermatopathology (Basel, Switzerland) (2022)
Our study failed to reveal possible TFE3 gene fusion by IHC staining in benign, atypical, and malignant chondroid syringomas. Although the negative staining in MCS suggests a genetic heterogeneity in this entity, further studies with larger case groups are needed for a more definitive conclusion.
Keyphrases
  • genome wide
  • single cell
  • copy number
  • flow cytometry
  • dna methylation
  • locally advanced
  • case control
  • radiation therapy