IgM response is a prognostic biomarker of primary biliary cholangitis treated with ursodeoxycholic acid and bezafibrate.
Keiko TakanoChisato SaekiTsunekazu OikawaAkihisa HidakaYusuke MizunoJinya IshidaKazuki TakakuraMasanori NakanoYuichi TorisuKatsushi AmanoTomohisa IshikawaMikio ZeniyaAkihito TsubotaMasayuki SarutaPublished in: Journal of gastroenterology and hepatology (2019)
Our findings point to the beneficial effects of long-term UDCA plus bezafibrate combination therapy for UDCA-refractory PBC patients, and IgM response can be a useful predictive biomarker of long-term clinical outcomes.