O6-methylguanine-DNA Methyltransferase Promoter Methylation in Patients with Rectal Adenocarcinoma After Chemoradiotherapy Treatment: Clinical Implications

Jaime A. OliverJaime Gómez-MillánJose A. MedinaLaura CabezaGloria PerazzoliCristina Jimenez-LunaKevin DoelloRaúl Ortiz

Published in: Balkan medical journal (2019)

O6-methylguanine-DNA methyltransferase methylation status is not correlated with clinicopathologic variables examined in rectal adenocarcinoma selected for chemoradiotherapy, although its role as a biomarker awaits further investigation.

Keyphrases

rectal cancer
locally advanced
dna methylation
circulating tumor
cell free
squamous cell carcinoma
single molecule
genome wide
gene expression
transcription factor
nucleic acid
combination therapy
replacement therapy