A prospective longitudinal analysis of the predictors of amenorrhea after breast cancer chemotherapy: Impact of BRCA pathogenic variants.

Kutluk H OktayVolkan TuranGiuliano BedoschiNadia AbdoHeejung BangShari Goldfarb

Published in: Cancer medicine (2023)

In addition to the pre- and post-treatment AMH levels, gBRCApv status is a novel potential predictor of amenorrhea at 12 and 18 months after chemotherapy. The higher likelihood of amenorrhea in women gBRCApv suggests that they are more prone to losing their fertility post-chemotherapy.

Keyphrases

locally advanced
breast cancer risk
squamous cell carcinoma
polycystic ovary syndrome
chemotherapy induced
type diabetes
rectal cancer
gene expression
pregnant women
climate change
childhood cancer
young adults